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Index > Protein center > Anpep(Gene name) > Rat
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  • Anpep (Gene name),
  • Aminopeptidase N (Protein name ),  AMPN_RAT from NCBI database.
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  • Gene name:
    Anpep;
    Protein name:
    Aminopeptidase N(AP-N;rAPN);
    Alternative:
    Aminopeptidase M(AP-M);Alanyl aminopeptidase;Microsomal aminopeptidase;Kidney Zn peptidase(KZP);
    CD:
    CD13;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May be involved in the metabolism of regulatory peptides of diverse cell types. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells. May have a role in angiogenesis.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    965
    Sequence:
    50:
    MAKGFYISKT | LGILGILLGV | AAVCTIIALS | VVYAQEKNRN | AENSAIAPTL | 
    100:
    PGSTSATTST | TNPAIDESKP | WNQYRLPKTL | IPDSYQVTLR | PYLTPNEQGL | 
    150:
    YIFKGSSTVR | FTCNETTNVI | IIHSKKLNYT | NKGNHRVALR | ALGDTPAPNI | 
    200:
    DTTELVERTE | YLVVHLQGSL | VKGHQYEMDS | EFQGELADDL | AGFYRSEYME | 
    250:
    GGNKKVVATT | QMQAADARKS | FPCFDEPAMK | ASFNITLIHP | NNLTALSNML | 
    300:
    PKDSRTLQED | PSWNVTEFHP | TPKMSTYLLA | YIVSEFKYVE | AVSPNRVQIR | 
    350:
    IWARPSAIDE | GHGDYALQVT | GPILNFFAQH | YNTAYPLEKS | DQIALPDFNA | 
    400:
    GAMENWGLVT | YRESALVFDP | QSSSISNKER | VVTVIAHELA | HQWFGNLVTV | 
    450:
    DWWNDLWLNE | GFASYVEFLG | ADYAEPTWNL | KDLIVLNDVY | RVMAVDALAS | 
    500:
    SHPLSSPANE | VNTPAQISEL | FDSITYSKGA | SVLRMLSSFL | TEDLFKKGLS | 
    550:
    SYLHTFQYSN | TIYLDLWEHL | QQAVDSQTAI | KLPASVSTIM | DRWILQMGFP | 
    600:
    VITVNTSTGE | IYQEHFLLDP | TSKPTRPSDF | NYLWIVPIPY | LKNGKEDHYW | 
    650:
    LETEKNQSAE | FQTSSNEWLL | LNINVTGYYQ | VNYDENNWRK | IQNQLQTDLS | 
    700:
    VIPVINRAQI | IHDSFNLASA | GKLSITLPLS | NTLFLASETE | YMPWEAALSS | 
    750:
    LNYFKLMFDR | SEVYGPMKRY | LKKQVTPLFA | YFKIKTNNWL | DRPPTLMEQY | 
    800:
    NEINAISTAC | SSGLEECRDL | VVGLYSQWMN | NSDNNPIHPN | LRSTVYCNAI | 
    850:
    AFGGEEEWNF | AWEQFRKATL | VNEADKLRSA | LACSNEVWIL | NRYLSYTLNP | 
    900:
    DYIRKQDATS | TIVSIANNVV | GQTLVWDFVR | SNWKKLFEDY | GGGSFSFANL | 
    950:
    IQGVTRRFSS | EFELQQLEQF | KEDNSATGFG | SGTRALEQAL | EKTKANIKWV | 
    965:
    KENKDVVLKW | FTENS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat AP-N
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    E9154m
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    96T
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    ELISA Kit for Rat AP-N
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    E9154h
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    96T
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    ELISA Kit for Rat AP-N
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    E9154p
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    96T
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    ELISA Kit for Rat AP-N
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    E9154c
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    ELISA Kit for Rat AP-N
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    E9154r
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    ELISA Kit for Rat AP-N
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    ELISA Kit for Rat AP-N
    Cat.:
    E9154d
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    96T
    ELISA Kit for Rat AP-N
    Cat.:
    E9154b
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    96T
    CLIA Kit for Rat AP-N
    Cat.:
    U9154p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat AP-N
    Cat.:
    U9154h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat AP-N
    Cat.:
    U9154m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat AP-N
    MSDS:
    Please sign in first.
    CLIA Kit for Rat AP-N
    Cat.:
    U9154d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat AP-N
    Cat.:
    U9154r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Rat AP-N
    Cat.:
    U9154b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat AP-N
    Cat.:
    U9154c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat AP-N
    Polyclonal Antibody for Rat AP-N
    Polyclonal Antibody for Rat AP-N
    Polyclonal Antibody for Rat AP-N
    Cat.:
    P9154Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AP-N
    Polyclonal Antibody for Rat AP-N
    Polyclonal Antibody for Rat AP-N
    Cat.:
    P9154Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AP-N
    Cat.:
    P9154Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Monoclonal Antibody for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N
    Protein for Rat AP-N

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    References
    1. 1.
      "Amino acid sequence deduced from a rat kidney cDNA suggests it encodes the Zn-peptidase aminopeptidase N."
      Watt V.M. , Yip C.C.
      J. Biol. Chem.264:5480-5487(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    2. 2.
      "Molecular cloning and amino acid sequence of rat kidney aminopeptidase M: a member of a super family of zinc-metallohydrolases."
      Malfroy B. , Kado-Fong H. , Gros C. , Giros B. , Schwartz J.C. , Hellmiss R.
      Biochem. Biophys. Res. Commun.161:236-241(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    3. 3.
      Gal-Gaber O.
      Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 198-754
    4. 4.
      "p146 type II alveolar epithelial cell antigen is identical to aminopeptidase N."
      Funkhouser J.D. , Tangada S.D. , Jones M. , O S.J. , Peterson R.D.
      Am. J. Physiol.260:L274-L279(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-19; 68-84; 206-215; 286-299 AND 364-371
    5. 5.
      "First discrete autoradiographic distribution of aminopeptidase N in various structures of rat brain and spinal cord using the selective iodinated inhibitor 125IRB 129."
      Noble F. , Banisadr G. , Jardinaud F. , Popovici T. , Lai-Kuen R. , Chen H. , Bischoff L. , Parsadaniantz S.M. , Fournie-Zaluski M.-C. , Roques B.P.
      Neuroscience105:479-488(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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